BDBM249382 US9464081, 15

SMILES [#6]-[#6]-c1cc2c(nn(-[#6]-[#6](=O)-[#7]-3-[#6@@H]-4-[#6]-[#6@@H]-4-[#6]-[#6@H]-3-[#6](=O)-[#7]-[#6]\[#6](F)=[#6](\[#6])-[#6])c2cn1)-[#6](-[#7])=O

InChI Key InChIKey=OUVZVZFYZSOOPG-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 249382   

TargetComplement factor D(Human)
Novartis

US Patent
LigandPNGBDBM249382(US9464081, 15)
Affinity DataIC50: 43nMpH: 7.5 T: 2°CAssay Description:Method 1: Recombinant human factor D (expressed in E. coli and purified using standard methods) at 10 nM concentration is incubated with test compoun...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/11/2017
Entry Details
Go to US Patent