BDBM249873 US10005782, Compound 1::US9447106, 1::US9556188, Compound 1

SMILES Nc1cccc(c1)-c1ccnc2c(C#N)c(nn12)-c1ccc(Oc2ccccc2)cc1

InChI Key InChIKey=UOVVHNPWWUMEHZ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 249873   

TargetTyrosine-protein kinase BTK(Human)
Beigene

US Patent
LigandPNGBDBM249873(US9447106, 1 | US9556188, Compound 1 | US10005782,...)
Affinity DataIC50: 1.00E+4nMT: 2°CAssay Description:Compounds disclosed herein were tested for inhibition of Btk kinase activity in an assay based on time-resolved fluorescence resonance energy transfe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2018
Entry Details
Go to US Patent

TargetTyrosine-protein kinase BTK(Human)
Beigene

US Patent
LigandPNGBDBM249873(US9447106, 1 | US9556188, Compound 1 | US10005782,...)
Affinity DataIC50: 1.00E+4nMT: 2°CAssay Description:Compounds disclosed herein were tested for inhibition of Btk kinase activity in an assay based on time-resolved fluorescence resonance energy transfe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/18/2017
Entry Details
Go to US Patent

TargetTyrosine-protein kinase BTK(Human)
Beigene

US Patent
LigandPNGBDBM249873(US9447106, 1 | US9556188, Compound 1 | US10005782,...)
Affinity DataIC50: 1.00E+4nMAssay Description:Compounds disclosed herein were tested for inhibition of Btk kinase activity in an assay based on time-resolved fluorescence resonance energy transfe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/18/2020
Entry Details
Go to US Patent