BDBM249904 US9447106, 31::US9556188, Compound 31

SMILES NC(=O)c1c2N[C@@H]3CCN(C[C@@H]3Cn2nc1-c1ccc(Oc2ccccc2)cc1)C(=O)C=C

InChI Key InChIKey=MLNUYJRXHKLHOE-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 249904   

TargetTyrosine-protein kinase BTK(Human)
Beigene

US Patent
LigandPNGBDBM249904(US9447106, 31 | US9556188, Compound 31)
Affinity DataIC50: 15nMT: 2°CAssay Description:Compounds disclosed herein were tested for inhibition of Btk kinase activity in an assay based on time-resolved fluorescence resonance energy transfe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2018
Entry Details
US Patent

TargetTyrosine-protein kinase BTK(Human)
Beigene

US Patent
LigandPNGBDBM249904(US9447106, 31 | US9556188, Compound 31)
Affinity DataIC50: 15nMT: 2°CAssay Description:Compounds disclosed herein were tested for inhibition of Btk kinase activity in an assay based on time-resolved fluorescence resonance energy transfe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/18/2017
Entry Details
US Patent