BDBM249911 US10005782, Compound 38::US9447106, 38::US9556188, Compound 38

SMILES NC(=O)c1c2NCC3(CCN(Cc4ccccc4)CC3)n2nc1-c1ccc(Oc2ccccc2)cc1

InChI Key InChIKey=DXJLQIGTGLOKRE-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 249911   

TargetTyrosine-protein kinase BTK(Human)
Beigene

US Patent
LigandPNGBDBM249911(US9447106, 38 | US9556188, Compound 38 | US1000578...)
Affinity DataIC50: 490nMT: 2°CAssay Description:Compounds disclosed herein were tested for inhibition of Btk kinase activity in an assay based on time-resolved fluorescence resonance energy transfe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2018
Entry Details
US Patent

TargetTyrosine-protein kinase BTK(Human)
Beigene

US Patent
LigandPNGBDBM249911(US9447106, 38 | US9556188, Compound 38 | US1000578...)
Affinity DataIC50: 490nMAssay Description:Compounds disclosed herein were tested for inhibition of Btk kinase activity in an assay based on time-resolved fluorescence resonance energy transfe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/18/2020
Entry Details
US Patent

TargetTyrosine-protein kinase BTK(Human)
Beigene

US Patent
LigandPNGBDBM249911(US9447106, 38 | US9556188, Compound 38 | US1000578...)
Affinity DataIC50: 490nMT: 2°CAssay Description:Compounds disclosed herein were tested for inhibition of Btk kinase activity in an assay based on time-resolved fluorescence resonance energy transfe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/18/2017
Entry Details
US Patent