BDBM251608 US9453031, 31

SMILES CNc1nc2ccccc2n1-c1nc2N3CCOCC3CCOc2c(n1)C(C)(C)S(C)(=O)=O

InChI Key InChIKey=MPXUUMJYLCHFAB-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 251608   

TargetPhosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Human)
FundacióN Centro Nacional De Investigaciones OncolóGicas Carlos Iii

US Patent
LigandPNGBDBM251608(US9453031, 31)
Affinity DataIC50: 6.50E+3nMpH: 7.5 T: 2°CAssay Description:The kinase activity was measured by using the commercial ADP Hunter Plus assay available from DiscoveRx (#33-016), which is a homogeneous assay to me...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2017
Entry Details
US Patent

TargetSerine/threonine-protein kinase mTOR [1360-2549](Human)
FundacióN Centro Nacional De Investigaciones OncolóGicas Carlos Iii

US Patent
LigandPNGBDBM251608(US9453031, 31)
Affinity DataIC50: 586nMpH: 7.5 T: 2°CAssay Description:The enzymatic mTOR activity was measured using a LanthaScreen kinase activity assay (Invitrogen). The enzyme was purchased from Invitrogen (PV4754), ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2017
Entry Details
US Patent

TargetDNA-dependent protein kinase catalytic subunit(Human)
FundacióN Centro Nacional De Investigaciones OncolóGicas Carlos Iii

US Patent
LigandPNGBDBM251608(US9453031, 31)
Affinity DataIC50: 1.88E+3nMpH: 7.5 T: 2°CAssay Description:The kinase activity was measured by using the commercial ADP Hunter Plus assay available from DiscoveRx (#90-0083), which is a homogeneous assay to m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2017
Entry Details
US Patent