BDBM251702 US10100018, Example 38::US9464060, 38

SMILES OC(=O)c1ccc(CN(CCC2CC2)C(=O)c2ccc(Oc3c(F)cccc3F)cc2)cc1

InChI Key InChIKey=GUCWMYPGSTXNQO-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 251702   

TargetLysophosphatidic acid receptor 1(Human)
Takeda Pharmaceutical

US Patent
LigandPNGBDBM251702(US9464060, 38 | US10100018, Example 38)
Affinity DataIC50: 140nMT: 2°CAssay Description:Engagement of the LPA1 receptor by its ligand, oleoyl-L-α-lysophosphatidic acid (LPA), leads to the release of intracellular stores of calcium i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2019
Entry Details
US Patent

TargetLysophosphatidic acid receptor 1(Human)
Takeda Pharmaceutical

US Patent
LigandPNGBDBM251702(US9464060, 38 | US10100018, Example 38)
Affinity DataIC50: 36nMT: 2°CAssay Description:Engagement of the LPA1 receptor by its ligand, oleoyl-L-α-lysophosphatidic acid (LPA), leads to the release of intracellular stores of calcium i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2019
Entry Details
US Patent

TargetLysophosphatidic acid receptor 5(Human)
Takeda Pharmaceutical

US Patent
LigandPNGBDBM251702(US9464060, 38 | US10100018, Example 38)
Affinity DataIC50: 140nMT: 2°CAssay Description:Engagement of the LPA5 receptor by its ligand, oleoyl-L- ±-lysophosphatidic acid (LPA), leads to the release of intracellular stores of calcium into ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2017
Entry Details
US Patent

TargetLysophosphatidic acid receptor 1(Human)
Takeda Pharmaceutical

US Patent
LigandPNGBDBM251702(US9464060, 38 | US10100018, Example 38)
Affinity DataIC50: 36nMT: 2°CAssay Description:Engagement of the LPA1 receptor by its ligand, oleoyl-L- ±-lysophosphatidic acid (LPA), leads to the release of intracellular stores of calcium into ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2017
Entry Details
US Patent