BDBM25452 3-[5-(4-fluorophenyl)-2,3-dihydro-1H-inden-1-yl]pyridine::Abiraterone mimetic, 15

SMILES Fc1ccc(cc1)-c1ccc2C(CCc2c1)c1cccnc1

InChI Key InChIKey=YTOSVNJINOPENX-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 25452   

TargetCytochrome P450 3A4(Human)
Saarland University

LigandPNGBDBM25452(3-[5-(4-fluorophenyl)-2,3-dihydro-1H-inden-1-yl]py...)
Affinity DataIC50: 1.70E+3nMAssay Description:The 17 alpha-hydroxylase activity of CYP 17 was determined by measuring the conversion of progesterone into 17 alpha-hydroxyprogesterone and the bypr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2008
Entry Details Article
PubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Human)
Saarland University

LigandPNGBDBM25452(3-[5-(4-fluorophenyl)-2,3-dihydro-1H-inden-1-yl]py...)
Affinity DataIC50: 2.00E+4nMpH: 7.4 T: 2°CAssay Description:The 17 alpha-hydroxylase activity of CYP 17 was determined by measuring the conversion of progesterone into 17 alpha-hydroxyprogesterone and the bypr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2008
Entry Details Article
PubMed