BDBM254522 US9468661, 100

SMILES CC(Oc1ccc2n(CC(=O)N3[C@@H]4C[C@@H]4C[C@H]3C(=O)NC[C@H]3CC3(Cl)Cl)nc(C(C)=O)c2c1)c1ncccn1

InChI Key InChIKey=VZEFVPHGWJPGBA-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 254522   

TargetComplement factor D(Human)
Novartis

US Patent
LigandPNGBDBM254522(US9468661, 100)
Affinity DataIC50: 158nMpH: 7.5 T: 2°CAssay Description:Method 1: Recombinant human factor D (expressed in E. coli and purified using standard methods) at 10 nM concentration is incubated with test compoun...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2017
Entry Details
US Patent