BDBM25541 7,8-dihydroxy-2-(hydroxymethyl)-5-methylphenanthridin-5-ium chloride::chelerythrine analogue, 43

SMILES Cn1cc2c(ccc(O)c2=[OH+])c2cc(CO)ccc12

InChI Key InChIKey=HCCAEKKZJRLJJL-UHFFFAOYSA-O

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 25541   

TargetBcl-2-like protein 1(Human)
A* Star

LigandPNGBDBM25541(7,8-dihydroxy-2-(hydroxymethyl)-5-methylphenanthri...)
Affinity DataIC50: 2.00E+4nMpH: 8.0 T: 2°CAssay Description:In the fluorescence polarization assay, the Bcl-XL protein is incubated with a fluorescein-tagged Bak-BH3 peptide. The Bcl-XL:Bak-BH3 peptide complex...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2008
Entry Details Article
PubMed