BDBM255541 US9499523, 15

SMILES C[C@H](Nc1nc(N)nc(N)c1C#N)c1nc2c(F)cc(F)cc2c(=O)n1-c1cnc(N)cn1

InChI Key InChIKey=GFFQKKWMLSGONS-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 255541   

LigandPNGBDBM255541(US9499523, 15)
Affinity DataIC50: 9.80nMpH: 7.4 T: 2°CAssay Description:The activities were measured using a time-resolved fluorescence resonance energy transfer (TR-FRET) assay. TR-FRET monitored the formation of 3,4,5-i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2017
Entry Details
US Patent

LigandPNGBDBM255541(US9499523, 15)
Affinity DataIC50: 53nMpH: 7.4 T: 2°CAssay Description:The activities were measured using a time-resolved fluorescence resonance energy transfer (TR-FRET) assay. TR-FRET monitored the formation of 3,4,5-i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2017
Entry Details
US Patent

LigandPNGBDBM255541(US9499523, 15)
Affinity DataIC50: 1.50E+3nMpH: 7.4 T: 2°CAssay Description:The activities were measured using a time-resolved fluorescence resonance energy transfer (TR-FRET) assay. TR-FRET monitored the formation of 3,4,5-i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2017
Entry Details
US Patent