BDBM256114 US9481672, 298

SMILES COC(=O)c1cn(-c2ccc3n(C)c(=O)sc3c2)c(=O)n([C@@H]2CCCc3c2cccc3C(F)(F)F)c1=O

InChI Key InChIKey=FMIYGYPLJJZJDU-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 256114   

Targetchymase(Golden hamster)
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM256114(US9481672, 298)
Affinity DataIC50: 6nMpH: 7.5Assay Description:The enzyme source used is recombinant human chymase (expressed in HEK293 cells) or chymase purified from hamsters' tongues. The substrate used for ch...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2017
Entry Details
US Patent