BDBM256399 US9487490, 9B

SMILES C[C@]1(CC[C@@H](CC1)c1nn(C(=O)c2c(Cl)cccc2C(F)(F)F)c2cccc(F)c12)C(O)=O

InChI Key InChIKey=OJVACVRAWQVAIH-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 256399   

TargetIsoform 2 of Nuclear receptor ROR-gamma (RORgT)(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM256399(US9487490, 9B)
Affinity DataIC50: 5.02E+3nMpH: 7.0 T: 2°CAssay Description:To identify novel antagonists of RORgammaT, an assay was developed which employs the interaction of RORgammaT with its co-activator peptide SRC1_2. T...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2017
Entry Details
Go to US Patent