BDBM25679 aminothiazole analogue, 23::ethyl 4-[(5-bromo-1,3-thiazol-2-yl)amino]benzoate

SMILES CCOC(=O)c1ccc(Nc2ncc(Br)s2)cc1

InChI Key InChIKey=UCNQZHJDGNKKCF-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 25679   

TargetAurora kinase A(Human)
Novartis

LigandPNGBDBM25679(ethyl 4-[(5-bromo-1,3-thiazol-2-yl)amino]benzoate ...)
Affinity DataIC50: 5.70E+3nMpH: 7.0 T: 2°CAssay Description:The biochemical activity of compounds was determined by incubation with Aurora A and substrates in the presence ATP/[gamma-33P] ATP. After incubatio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2008
Entry Details Article
PubMed