BDBM257829 US9493446, 298

SMILES FC(F)(F)Oc1ccccc1-c1noc(n1)[C@@H]1CCCN1C(=O)c1cccc(Cl)c1-n1nccn1

InChI Key InChIKey=CTUDLPIJFWUKCK-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 257829   

TargetOrexin receptor type 2(Human)
Actelion Pharmaceuticals

US Patent
LigandPNGBDBM257829(US9493446, 298)
Affinity DataIC50: 517nMT: 2°CAssay Description:Human orexin-A as an agonist is prepared as 1 mM stock solution in MeOH: water (1:1), diluted in HBSS containing 0.1% bovine serum albumin (BSA), NaH...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2017
Entry Details
US Patent

TargetOrexin/Hypocretin receptor type 1(Human)
Actelion Pharmaceuticals

US Patent
LigandPNGBDBM257829(US9493446, 298)
Affinity DataIC50: 531nMT: 2°CAssay Description:Human orexin-A as an agonist is prepared as 1 mM stock solution in MeOH: water (1:1), diluted in HBSS containing 0.1% bovine serum albumin (BSA), NaH...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2017
Entry Details
US Patent