BDBM257929 US9493446, 398

SMILES CCc1ccccc1-c1nc(no1)[C@@H]1CCCN1C(=O)c1ccc(Cl)cc1-n1nccn1

InChI Key InChIKey=KNKZHYJZNLJPTJ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 257929   

TargetOrexin/Hypocretin receptor type 1(Human)
Actelion Pharmaceuticals

US Patent
LigandPNGBDBM257929(US9493446, 398)
Affinity DataIC50: 33nMT: 2°CAssay Description:Human orexin-A as an agonist is prepared as 1 mM stock solution in MeOH: water (1:1), diluted in HBSS containing 0.1% bovine serum albumin (BSA), NaH...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2017
Entry Details
US Patent

TargetOrexin receptor type 2(Human)
Actelion Pharmaceuticals

US Patent
LigandPNGBDBM257929(US9493446, 398)
Affinity DataIC50: 18nMT: 2°CAssay Description:Human orexin-A as an agonist is prepared as 1 mM stock solution in MeOH: water (1:1), diluted in HBSS containing 0.1% bovine serum albumin (BSA), NaH...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2017
Entry Details
US Patent