BDBM258526 US10633384, Example 6.5::US9493486, 6.5

SMILES Fc1cc(F)cc(c1)[C@@H]1C[C@H]1C(=O)N1CCC2(CN(C2)C(=O)c2ccc3[nH]nnc3c2)CC1

InChI Key InChIKey=CKPDEKDDHGCAJB-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 258526   

TargetAutotaxin(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM258526(US9493486, 6.5 | US10633384, Example 6.5)
Affinity DataIC50: 3.22E+3nMpH: 8.0 T: 2°CAssay Description:ATX inhibition was measured by a fluorescence quenching assay using a specifically labeled substrate analogue (MR121 substrate). To obtain this MR121...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2017
Entry Details
US Patent

TargetAutotaxin(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM258526(US9493486, 6.5 | US10633384, Example 6.5)
Affinity DataIC50: 3.22E+3nMAssay Description:ATX inhibition was measured by a fluorescence quenching assay using a specifically labeled substrate analogue (MR121 substrate). To obtain this MR121...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/12/2021
Entry Details
US Patent