BDBM259354 US9505745, 31::US9790212, Example 31

SMILES CCN(C1CCOCC1)c1scc(C(=O)NCc2c(C)cc(C)n(C)c2=O)c1C

InChI Key InChIKey=VSNXIWYGHMHREB-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 259354   

LigandPNGBDBM259354(US9505745, 31 | US9790212, Example 31)
Affinity DataIC50: 100nMAssay Description:Protocol 1: Compounds contained herein were evaluated for their ability to inhibit the methyltransferase activity of EZH2 within the PRC2 complex. Hu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2017
Entry Details
US Patent

LigandPNGBDBM259354(US9505745, 31 | US9790212, Example 31)
Affinity DataIC50: 100nMAssay Description:Compounds contained herein were evaluated for their ability to inhibit the methyltransferase activity of EZH2 within the PRC2 complex. Human PRC2 com...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2019
Entry Details
US Patent

LigandPNGBDBM259354(US9505745, 31 | US9790212, Example 31)
Affinity DataIC50: 794nMAssay Description:Protocol 2: Compounds contained herein were evaluated for their ability to inhibit the methyltransferase activity of EZH2 within the PRC2 complex. Hu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2017
Entry Details
US Patent

LigandPNGBDBM259354(US9505745, 31 | US9790212, Example 31)
Affinity DataIC50: 794nMAssay Description:Compounds contained herein were evaluated for their ability to inhibit the methyltransferase activity of EZH2 within the PRC2 complex. Human PRC2 com...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2019
Entry Details
US Patent