BDBM26075 2-benzyl-3-aryl-7-trifluoromethylindazole, 21::3-(4-chlorophenyl)-7-(trifluoromethyl)-2-{[2-(trifluoromethyl)phenyl]methyl}-2H-indazole

SMILES FC(F)(F)c1ccccc1Cn1nc2c(cccc2c1-c1ccc(Cl)cc1)C(F)(F)F

InChI Key InChIKey=CDLBQZJYZMCUBN-UHFFFAOYSA-N

Data  2 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 26075   

TargetOxysterols receptor LXR-alpha [197-447](Homo sapiens (Human))
Wyeth Research

LigandPNGBDBM26075(2-benzyl-3-aryl-7-trifluoromethylindazole, 21 | 3-...)
Affinity DataIC50:  465nM EC50:  1.58E+4nMAssay Description:Binding reaction was initiated by adding a dilution series of test compound in tracer solution to LXR-coated flash plates. Each concentration of test...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxysterols receptor LXR-beta [154-461](Homo sapiens (Human))
Wyeth Research

LigandPNGBDBM26075(2-benzyl-3-aryl-7-trifluoromethylindazole, 21 | 3-...)
Affinity DataIC50:  48nM EC50:  1.55E+4nMpH: 7.4 T: 2°CAssay Description:Binding reaction was initiated by adding a dilution series of test compound in tracer solution to LXR-coated flash plates. Each concentration of test...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed