BDBM261275 US11433071, Example 298-1::US9707233, 298 (1st peak)

SMILES CCN1CC(C1)c1c(Cl)c(Cl)cc([C@@H](C)n2nc(C)c3c(N)ncnc23)c1OC

InChI Key InChIKey=RMFYBQIIKKPTTD-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 261275   

LigandPNGBDBM261275(US9707233, 298 (1st peak) | US11433071, Example 29...)
Affinity DataIC50: 10nMpH: 6.7 T: 2°CAssay Description:Lipid kinase substrate, phosphoinositol-4,5-bisphosphate (PIP2), are purchased from Echelon Biosciences (Salt Lake City, Utah). PI3K isoforms α,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2018
Entry Details
US Patent

LigandPNGBDBM261275(US9707233, 298 (1st peak) | US11433071, Example 29...)
Affinity DataIC50: 10nMAssay Description:The kinase reaction was conducted in polystyrene 384-well matrix white plate from Thermo Fisher Scientific in a final volume of 25 μL. Inhibitor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2022
Entry Details
US Patent