BDBM261670 US9708279, 47::isopropyl 2-((4-((4-(3-((triisopropylsilyl)ethynyl)phenyl)thiazol-2-yl)carbamoyl)benzyl)amino)acetate

SMILES CC(C)OC(=O)CNCc1ccc(cc1)C(=O)Nc1nc(cs1)-c1cccc(c1)C#C[Si](C(C)C)(C(C)C)C(C)C

InChI Key InChIKey=FSKLVOXUVBKVGP-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 261670   

TargetALK tyrosine kinase receptor [L1196M](Homo sapiens (Human))
UniversitÁ

US Patent
LigandPNGBDBM261670(US9708279, 47 | isopropyl 2-((4-((4-(3-((triisopro...)
Affinity DataIC50: >1.00E+5nMpH: 7.5 T: 2°CAssay Description:GST-tagged recombinant wild-type or L1196M mutated ALK kinase (rALK) was expressed in Sf9 insect cells using the pBacPAK baculovirus vector system (C...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
UniversitÁ

US Patent
LigandPNGBDBM261670(US9708279, 47 | isopropyl 2-((4-((4-(3-((triisopro...)
Affinity DataIC50:  4.60E+4nMpH: 7.5 T: 2°CAssay Description:GST-tagged recombinant wild-type or L1196M mutated ALK kinase (rALK) was expressed in Sf9 insect cells using the pBacPAK baculovirus vector system (C...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent