BDBM262511 3-methyl-N-{[3'-sulfamoyl- 2'-(1H-tetrazol-5- yl)biphenyl-4-yl]methyl}-D- histidine::US9708336, 363

SMILES Cn1cncc1C[C@@H](NCc1ccc(cc1)-c1cccc(c1-c1nnn[nH]1)S(N)(=O)=O)C(O)=O

InChI Key InChIKey=PMSJZTRJNFCRAV-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 262511   

TargetMetallo-beta-lactamase type 2(Pseudomonas aeruginosa (g-Proteobacteria))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM262511(US9708336, 363 | 3-methyl-N-{[3'-sulfamoyl- 2'-(1H...)
Affinity DataIC50: 21.4nMpH: 7.0Assay Description:The Class B enzyme activities were measured in the presence of the test inhibitor in a fluorescence assay against a commercially available substrate ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/5/2018
Entry Details
US Patent

TargetMetallo-beta-lactamase type 2(Serratia marcescens)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM262511(US9708336, 363 | 3-methyl-N-{[3'-sulfamoyl- 2'-(1H...)
Affinity DataIC50: 233nMpH: 7.0Assay Description:The Class B enzyme activities were measured in the presence of the test inhibitor in a fluorescence assay against a commercially available substrate ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/5/2018
Entry Details
US Patent

TargetVIM-1 metallo-beta-lactamase(Pseudomonas aeruginosa (g-Proteobacteria))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM262511(US9708336, 363 | 3-methyl-N-{[3'-sulfamoyl- 2'-(1H...)
Affinity DataIC50: 495nMpH: 7.0Assay Description:The Class B enzyme activities were measured in the presence of the test inhibitor in a fluorescence assay against a commercially available substrate ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/5/2018
Entry Details
US Patent