BDBM263397 US9550741, II-7

SMILES O=S(=O)(N[C@H]1CC[C@H](CCN2CCN(CC2)c2nsc3ccccc23)CC1)c1ccc(o1)[N+]#[C-]

InChI Key InChIKey=FJGIJPVLRUOQFB-UHFFFAOYSA-N

Data  11 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 11 hits for monomerid = 263397   

Target5-hydroxytryptamine receptor 1A(Human)
Shanghai Institute of Pharmaceutical Industry

US Patent
LigandPNGBDBM263397(US9550741, II-7)
Affinity DataKi:  2.10nMpH: 7.4Assay Description:1. Experimental Materials:The isotopic ligand of 5-H1A receptor [3H]0.8-OH-DPAT (purchased from PE Corporation), (+)5-hydroxytryptamine (purchased fr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2018
Entry Details
US Patent

Target5-hydroxytryptamine receptor 2A(Human)
Shanghai Institute of Pharmaceutical Industry

US Patent
LigandPNGBDBM263397(US9550741, II-7)
Affinity DataKi:  2.10nMpH: 7.7Assay Description:1. Experimental Materials(1) 5-HT2A Cell Transfection:This experiment utilizes the plasmid vector containing the gene of the 5-HT2A receptor protein ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2018
Entry Details
US Patent

Target5-hydroxytryptamine receptor 2A(Human)
Shanghai Institute of Pharmaceutical Industry

US Patent
LigandPNGBDBM263397(US9550741, II-7)
Affinity DataKi:  2.10nMpH: 7.7Assay Description:1. Experimental Materials(1) 5-HT2A Cell Transfection:This experiment utilizes the plasmid vector containing the gene of the 5-HT2A receptor protein ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2018
Entry Details
US Patent

Target5-hydroxytryptamine receptor 1A(Human)
Shanghai Institute of Pharmaceutical Industry

US Patent
LigandPNGBDBM263397(US9550741, II-7)
Affinity DataKi:  6.08nMpH: 7.4Assay Description:1. Experimental Materials:The isotopic ligand of 5-H1A receptor [3H]0.8-OH-DPAT (purchased from PE Corporation), (+)5-hydroxytryptamine (purchased fr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2018
Entry Details
US Patent

Target5-hydroxytryptamine receptor 1A(Human)
Shanghai Institute of Pharmaceutical Industry

US Patent
LigandPNGBDBM263397(US9550741, II-7)
Affinity DataKi:  6.08nMpH: 7.4Assay Description:1. Experimental Materials:The isotopic ligand of 5-H1A receptor [3H]0.8-OH-DPAT (purchased from PE Corporation), (+)5-hydroxytryptamine (purchased fr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2018
Entry Details
US Patent

TargetVitamin D3 receptor(Human)
Shanghai Institute of Pharmaceutical Industry

US Patent
LigandPNGBDBM263397(US9550741, II-7)
Affinity DataKi:  8.19nMAssay Description:The experiment is carried out by the method according to Journal of Pharmacology and Experimental Therapeutics 2010, 333(1): 328. With [3H]methyl-spi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2018
Entry Details
US Patent

TargetVitamin D3 receptor(Human)
Shanghai Institute of Pharmaceutical Industry

US Patent
LigandPNGBDBM263397(US9550741, II-7)
Affinity DataKi:  8.19nMAssay Description:The experiment is carried out by the method according to Journal of Pharmacology and Experimental Therapeutics 2010, 333(1): 328. With [3H]methyl-spi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2018
Entry Details
US Patent

TargetD(2) dopamine receptor(Human)
Shanghai Institute of Pharmaceutical Industry

US Patent
LigandPNGBDBM263397(US9550741, II-7)
Affinity DataKi:  8.54nMpH: 7.5Assay Description:1. Experimental Materials:(1) D2 receptor Cell Transfection:This experiment utilizes the plasmid vector containing the gene of D2 receptor protein fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2018
Entry Details
US Patent

TargetD(2) dopamine receptor(Human)
Shanghai Institute of Pharmaceutical Industry

US Patent
LigandPNGBDBM263397(US9550741, II-7)
Affinity DataKi:  8.54nMpH: 7.5Assay Description:1. Experimental Materials:(1) D2 receptor Cell Transfection:This experiment utilizes the plasmid vector containing the gene of D2 receptor protein fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2018
Entry Details
US Patent

Target5-hydroxytryptamine receptor 2A(Human)
Shanghai Institute of Pharmaceutical Industry

US Patent
LigandPNGBDBM263397(US9550741, II-7)
Affinity DataKi:  10.7nMpH: 7.7Assay Description:1. Experimental Materials(1) 5-HT2A Cell Transfection:This experiment utilizes the plasmid vector containing the gene of the 5-HT2A receptor protein ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2018
Entry Details
US Patent

Target5-hydroxytryptamine receptor 2A(Human)
Shanghai Institute of Pharmaceutical Industry

US Patent
LigandPNGBDBM263397(US9550741, II-7)
Affinity DataKi:  10.7nMpH: 7.7Assay Description:1. Experimental Materials(1) 5-HT2A Cell Transfection:This experiment utilizes the plasmid vector containing the gene of the 5-HT2A receptor protein ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2018
Entry Details
US Patent