BDBM264080 2-[3-[(4-chlorophenyl)methyl]-5- hydroxypyrazol-1-yl]pyridine-4- carboxylic acid::US10173996, Example 165::US9604961, Example 165::US9714230, 165::US9908865, Example 165

SMILES OC(=O)c1ccnc(c1)-n1nc(Cc2ccc(Cl)cc2)cc1O

InChI Key InChIKey=XJLXJKCXWBHULD-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 264080   

TargetLysine-specific demethylase 2B(Human)
Celgene Quanticel Research

US Patent
LigandChemical structure of BindingDB Monomer ID 264080BDBM264080(2-[3-[(4-chlorophenyl)methyl]-5- hydroxypyrazol-1-...)
Affinity DataIC50: 100nMAssay Description:The ability of test compounds to inhibit the activity of FBXL10 was determined in 384-well plate format under the following reaction conditions: 0.3 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/27/2020
Entry Details
US Patent

TargetLysine-specific demethylase 5B(Human)
Celgene Quanticel Research

US Patent
LigandChemical structure of BindingDB Monomer ID 264080BDBM264080(2-[3-[(4-chlorophenyl)methyl]-5- hydroxypyrazol-1-...)
Affinity DataIC50: 550nMAssay Description:The ability of test compounds to inhibit the activity of Jarid1B was determined in 384-well plate format under the following reaction conditions: 0.8...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/27/2020
Entry Details
US Patent

TargetLysine-specific demethylase 4C(Human)
Celgene Quanticel Research

US Patent
LigandChemical structure of BindingDB Monomer ID 264080BDBM264080(2-[3-[(4-chlorophenyl)methyl]-5- hydroxypyrazol-1-...)
Affinity DataIC50: 5.50E+3nMAssay Description:The ability of test compounds to inhibit the activity of JMJD2C was determined in 384-well plate format under the following reaction conditions: 0.3 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/27/2020
Entry Details
US Patent

TargetLysine-specific demethylase 4A(Human)
Celgene Quanticel Research

US Patent
LigandChemical structure of BindingDB Monomer ID 264080BDBM264080(2-[3-[(4-chlorophenyl)methyl]-5- hydroxypyrazol-1-...)
Affinity DataIC50: 1.00E+4nMAssay Description:The ability of test compounds to inhibit the activity of JMJD2A was determined in 38-well plate format under the following reaction conditions: 2 nM ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/27/2020
Entry Details
US Patent