BDBM264282 US9714247, 3

SMILES CCN(CC)CCOc1cnc(Nc2cc3n(CC)c(=O)c(cc3cn2)-c2ccccc2)nc1

InChI Key InChIKey=ZPQFVLUIQYTDSU-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 264282   

TargetProto-oncogene tyrosine-protein kinase Src(Human)
Tolero Pharmaceuticals

US Patent
LigandPNGBDBM264282(US9714247, 3)
Affinity DataIC50: 3.00E+3nMAssay Description:A concentration of a drug that reduces the observed activity of an enzyme by 50%. An IC50 is not a true affinity constant and the specific value dete...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/15/2018
Entry Details
US Patent

TargetTyrosine-protein kinase BTK(Human)
Tolero Pharmaceuticals

US Patent
LigandPNGBDBM264282(US9714247, 3)
Affinity DataIC50: 3.00E+3nMAssay Description:A concentration of a drug that reduces the observed activity of an enzyme by 50%. An IC50 is not a true affinity constant and the specific value dete...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/15/2018
Entry Details
US Patent

TargetTyrosine-protein kinase Lyn(Human)
Tolero Pharmaceuticals

US Patent
LigandPNGBDBM264282(US9714247, 3)
Affinity DataIC50: 5.00E+3nMAssay Description:A concentration of a drug that reduces the observed activity of an enzyme by 50%. An IC50 is not a true affinity constant and the specific value dete...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/15/2018
Entry Details
US Patent