BDBM264310 US9714247, 31

SMILES CCn1c2cc(Nc3ccc(C)cn3)ncc2cc(C2CCCC2)c1=O

InChI Key InChIKey=MEKGHWTWNAOJPB-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 264310   

TargetTyrosine-protein kinase BTK(Human)
Tolero Pharmaceuticals

US Patent
LigandPNGBDBM264310(US9714247, 31)
Affinity DataIC50: 5.00E+3nMAssay Description:A concentration of a drug that reduces the observed activity of an enzyme by 50%. An IC50 is not a true affinity constant and the specific value dete...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/15/2018
Entry Details
US Patent

TargetProto-oncogene tyrosine-protein kinase Src(Human)
Tolero Pharmaceuticals

US Patent
LigandPNGBDBM264310(US9714247, 31)
Affinity DataIC50: 550nMAssay Description:A concentration of a drug that reduces the observed activity of an enzyme by 50%. An IC50 is not a true affinity constant and the specific value dete...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/15/2018
Entry Details
US Patent

TargetTyrosine-protein kinase Lyn(Human)
Tolero Pharmaceuticals

US Patent
LigandPNGBDBM264310(US9714247, 31)
Affinity DataIC50: 5.00E+3nMAssay Description:A concentration of a drug that reduces the observed activity of an enzyme by 50%. An IC50 is not a true affinity constant and the specific value dete...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/15/2018
Entry Details
US Patent