BDBM267466 US9718822, 43-B::US9750744, Example 43-B::US9902741, Example 43-B

SMILES O[C@@H]1C[C@@H]2N(C1)c1ccn3ncc(C(=O)NCCOc4ccc(F)cc24)c3n1

InChI Key InChIKey=GAULVBGMKYMLPM-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 267466   

TargetHigh affinity nerve growth factor receptor(Human)
Array Biopharma

US Patent
LigandPNGBDBM267466(US9718822, 43-B | US9750744, Example 43-B | US9902...)
Affinity DataIC50: 1.55E+3nMpH: 7.5Assay Description:The ability of a compound to bind to TrkA was measured by Invitrogen's LanthaScreen Eu Kinase Binding Assay. In this assay, His-tagged recombinan...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2018
Entry Details
US Patent

TargetHigh affinity nerve growth factor receptor(Human)
Array Biopharma

US Patent
LigandPNGBDBM267466(US9718822, 43-B | US9750744, Example 43-B | US9902...)
Affinity DataIC50: 1.00E+3nMAssay Description:The ability of a compound to bind to TrkA was measured by Invitrogen's LanthaScreen Eu Kinase Binding Assay. In this assay, His-tagged recombinan...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2019
Entry Details
US Patent

TargetHigh affinity nerve growth factor receptor(Human)
Array Biopharma

US Patent
LigandPNGBDBM267466(US9718822, 43-B | US9750744, Example 43-B | US9902...)
Affinity DataIC50: 1.55E+3nMAssay Description:The ability of a compound to bind to TrkA was measured by Invitrogen's LanthaScreen Eu Kinase Binding Assay. In this assay, His-tagged recombinan...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/21/2020
Entry Details
US Patent