BDBM268142 2-(morpholin-4-yl)-4-(3-oxa-8-azabicyclo[33.2.1]oct-8-yl)-8-(1H-pyrazol-5-yl)-1,7-naphthyridine::US9549932, 174

SMILES C1CC2COCC1N2c1cc(nc2c(nccc12)-c1ccnn1C1CCCCO1)N1CCOCC1

InChI Key InChIKey=MHGFOOSVCGXJJU-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 268142   

TargetSerine/threonine-protein kinase ATR(Human)
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM268142(2-(morpholin-4-yl)-4-(3-oxa-8-azabicyclo[33.2.1]oc...)
Affinity DataIC50: 213nMpH: 7.0Assay Description:To determine of binding activity of the test compounds, full-length human ATR protein was expressed and purified together with ATRIP as described abo...More data for this Ligand-Target Pair
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Date in BDB:
11/29/2018
Entry Details
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