BDBM268591 N-(6-cyclopropyl-7-((6-methylspiro[2.5]octan-6-yl)methoxy)-[1,2,4]triazolo[4,3-a]pyridin-3-yl)cyclopropanesulfonamide::US9550775, 114

SMILES CC1(COc2cc3nnc(NS(=O)(=O)C4CC4)n3cc2C2CC2)CCC2(CC2)CC1

InChI Key InChIKey=QQZIQRMJSICMCT-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 268591   

TargetSodium channel protein type 9 subunit alpha(Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 268591BDBM268591(N-(6-cyclopropyl-7-((6-methylspiro[2.5]octan-6-yl)...)
Affinity DataIC50: 8nMpH: 7.2Assay Description:The following patch voltage clamp electrophysiology studies were performed on representative compounds of the invention using human embryonic kidney ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2018
Entry Details
US Patent