BDBM268691 US9718825, Example 93

SMILES Cc1n[nH]c2nc(ncc12)-c1ccc(NS(=O)(=O)c2cc(C)ccc2C#N)cc1

InChI Key InChIKey=GUDMFBIIEZHIFJ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 268691   

TargetSerine/threonine-protein kinase Sgk1(Human)
Sanofi

US Patent
LigandPNGBDBM268691(US9718825, Example 93)
Affinity DataIC50: 2.40E+3nMpH: 7.4Assay Description:The compounds were tested for serum and glucocorticoid-regulated kinase 1 (SGK-1) inhibitory activity in a substrate phosphorylation assay designed t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2018
Entry Details
Go to US Patent