BDBM271641 US10065941, Compound I-142

SMILES COC(=O)[C@@H](C)Cn1c(=O)[nH]\c(=N/c2ccc(Oc3ccccn3)cc2)n(C[C@H]2CC[C@H](C)CC2)c1=O

InChI Key InChIKey=RVCCGIPBVUETMM-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 271641   

TargetP2X purinoceptor 3(Human)
Shionogi

US Patent
LigandPNGBDBM271641(US10065941, Compound I-142)
Affinity DataIC50: 7nMpH: 7.5Assay Description:Stably expressing cell line (C6BU-1 cell transfected with human P2X3 receptor gene (GenBank accession number Y07683) was used. The cells were seeded ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2018
Entry Details
US Patent