BDBM272095 E1-(abs)-5-(3-Fluoro-2-methylphenyl)-N-hydroxy-1- phenyl-4,5,6,7-tetrahydro-1H-indazole-5-carboxamide::US10065948, 31::US10065948, 32::US10457675, Example 32

SMILES Cc1c(F)cccc1C1(CCc2c(C1)cnn2-c1ccccc1)C(=O)NO

InChI Key InChIKey=BCXPUIJBVOXQPU-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 272095   

TargetHistone deacetylase 9(Human)
Chdi Foundation

US Patent
LigandPNGBDBM272095(US10065948, 32 | E1-(abs)-5-(3-Fluoro-2-methylphen...)
Affinity DataIC50: 820nMAssay Description:The potency of the compounds is quantified by measuring the Histone Deacetylase 9 (HDAC9) enzymatic activity using the fluorogenic substrate, Boc-Lys...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2020
Entry Details
US Patent

TargetHistone deacetylase 9(Human)
Chdi Foundation

US Patent
LigandPNGBDBM272095(US10065948, 32 | E1-(abs)-5-(3-Fluoro-2-methylphen...)
Affinity DataIC50: 820nMAssay Description:The potency of the compounds is quantified by measuring the Histone Deacetylase 9 (HDAC9) enzymatic activity using the fluorogenic substrate, Boc-Lys...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2018
Entry Details
US Patent

TargetHistone deacetylase 9(Human)
Chdi Foundation

US Patent
LigandPNGBDBM272095(US10065948, 32 | E1-(abs)-5-(3-Fluoro-2-methylphen...)
Affinity DataIC50: 1.73E+4nMAssay Description:The potency of the compounds is quantified by measuring the Histone Deacetylase 9 (HDAC9) enzymatic activity using the fluorogenic substrate, Boc-Lys...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2020
Entry Details
US Patent

TargetHistone deacetylase 9(Human)
Chdi Foundation

US Patent
LigandPNGBDBM272095(US10065948, 32 | E1-(abs)-5-(3-Fluoro-2-methylphen...)
Affinity DataIC50: 1.73E+4nMAssay Description:The potency of the compounds is quantified by measuring the Histone Deacetylase 9 (HDAC9) enzymatic activity using the fluorogenic substrate, Boc-Lys...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2018
Entry Details
US Patent