BDBM272101 E1-(abs)-5-(3-Fluoro-2-methylphenyl)-N-hydroxy-1- (o-tolyl)-4,5,6,7-tetrahydro-1H-indazole-5- carboxamide::US10065948, 37::US10065948, 38::US10457675, Example 38

SMILES Cc1ccccc1-n1ncc2CC(CCc12)(C(=O)NO)c1cccc(F)c1C

InChI Key InChIKey=CSGXPITYMGMXLI-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 272101   

TargetHistone deacetylase 9(Human)
Chdi Foundation

US Patent
LigandPNGBDBM272101(E1-(abs)-5-(3-Fluoro-2-methylphenyl)-N-hydroxy-1- ...)
Affinity DataIC50: 1.10E+3nMAssay Description:The potency of the compounds is quantified by measuring the Histone Deacetylase 9 (HDAC9) enzymatic activity using the fluorogenic substrate, Boc-Lys...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2018
Entry Details
US Patent

TargetHistone deacetylase 9(Human)
Chdi Foundation

US Patent
LigandPNGBDBM272101(E1-(abs)-5-(3-Fluoro-2-methylphenyl)-N-hydroxy-1- ...)
Affinity DataIC50: 7.90E+3nMAssay Description:The potency of the compounds is quantified by measuring the Histone Deacetylase 9 (HDAC9) enzymatic activity using the fluorogenic substrate, Boc-Lys...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2018
Entry Details
US Patent

TargetHistone deacetylase 9(Human)
Chdi Foundation

US Patent
LigandPNGBDBM272101(E1-(abs)-5-(3-Fluoro-2-methylphenyl)-N-hydroxy-1- ...)
Affinity DataIC50: 1.10E+3nMAssay Description:The potency of the compounds is quantified by measuring the Histone Deacetylase 9 (HDAC9) enzymatic activity using the fluorogenic substrate, Boc-Lys...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2020
Entry Details
US Patent

TargetHistone deacetylase 9(Human)
Chdi Foundation

US Patent
LigandPNGBDBM272101(E1-(abs)-5-(3-Fluoro-2-methylphenyl)-N-hydroxy-1- ...)
Affinity DataIC50: 7.90E+3nMAssay Description:The potency of the compounds is quantified by measuring the Histone Deacetylase 9 (HDAC9) enzymatic activity using the fluorogenic substrate, Boc-Lys...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2020
Entry Details
US Patent