BDBM272125 E1-(abs)-5-(3-Fluoro-2-methylphenyl)-2-(2- fluorophenyl)-N-hydroxy-5,6-dihydro-4H- cyclopenta[d]thiazole-5-carboxamide::US10065948, 61::US10065948, 62::US10457675, Example 62

SMILES Cc1c(F)cccc1C1(Cc2nc(sc2C1)-c1ccccc1F)C(=O)NO

InChI Key InChIKey=FQFHAQRYBDVSDI-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 272125   

TargetHistone deacetylase 9(Human)
Chdi Foundation

US Patent
LigandPNGBDBM272125(E1-(abs)-5-(3-Fluoro-2-methylphenyl)-2-(2- fluorop...)
Affinity DataIC50: 193nMAssay Description:The potency of the compounds is quantified by measuring the Histone Deacetylase 9 (HDAC9) enzymatic activity using the fluorogenic substrate, Boc-Lys...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2020
Entry Details
Go to US Patent

TargetHistone deacetylase 9(Human)
Chdi Foundation

US Patent
LigandPNGBDBM272125(E1-(abs)-5-(3-Fluoro-2-methylphenyl)-2-(2- fluorop...)
Affinity DataIC50: 193nMAssay Description:The potency of the compounds is quantified by measuring the Histone Deacetylase 9 (HDAC9) enzymatic activity using the fluorogenic substrate, Boc-Lys...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2018
Entry Details
Go to US Patent

TargetHistone deacetylase 9(Human)
Chdi Foundation

US Patent
LigandPNGBDBM272125(E1-(abs)-5-(3-Fluoro-2-methylphenyl)-2-(2- fluorop...)
Affinity DataIC50: 480nMAssay Description:The potency of the compounds is quantified by measuring the Histone Deacetylase 9 (HDAC9) enzymatic activity using the fluorogenic substrate, Boc-Lys...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2020
Entry Details
Go to US Patent

TargetHistone deacetylase 9(Human)
Chdi Foundation

US Patent
LigandPNGBDBM272125(E1-(abs)-5-(3-Fluoro-2-methylphenyl)-2-(2- fluorop...)
Affinity DataIC50: 480nMAssay Description:The potency of the compounds is quantified by measuring the Histone Deacetylase 9 (HDAC9) enzymatic activity using the fluorogenic substrate, Boc-Lys...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2018
Entry Details
Go to US Patent