BDBM272145 E2-(abs)-5-(3-fluoro-2-methylphenyl)-N-hydroxy-3- phenyl-5,6-dihydro-4H-cyclopenta[d]isothiazole-5- carboxamide::US10065948, 81::US10457675, Example 81

SMILES Cc1c(F)cccc1[C@]1(Cc2snc(c2C1)-c1ccccc1)C(=O)NO

InChI Key InChIKey=IPSRBEYDLALGLY-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 272145   

TargetHistone deacetylase 9(Human)
Chdi Foundation

US Patent
LigandPNGBDBM272145(E2-(abs)-5-(3-fluoro-2-methylphenyl)-N-hydroxy-3- ...)
Affinity DataIC50: 9.70E+3nMAssay Description:The potency of the compounds is quantified by measuring the Histone Deacetylase 9 (HDAC9) enzymatic activity using the fluorogenic substrate, Boc-Lys...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2018
Entry Details
US Patent

TargetHistone deacetylase 9(Human)
Chdi Foundation

US Patent
LigandPNGBDBM272145(E2-(abs)-5-(3-fluoro-2-methylphenyl)-N-hydroxy-3- ...)
Affinity DataIC50: 9.70E+3nMAssay Description:The potency of the compounds is quantified by measuring the Histone Deacetylase 9 (HDAC9) enzymatic activity using the fluorogenic substrate, Boc-Lys...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2020
Entry Details
US Patent