BDBM274638 N-(6-(2-(4-fluorophenyl) imidazo[1,2-a]pyridin-3-yl) imidazo[1,2-b]pyridazin-2- yl)-3H-imidazo[4,5-b] pyridine-7-carboxamide::US9556179, Compound 213

SMILES Fc1ccc(cc1)-c1nc2ccccn2c1-c1ccc2nc(NC(=O)c3ccnc4[nH]cnc34)cn2n1

InChI Key InChIKey=GZTRSCWHPFORRZ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 274638   

TargetCasein kinase I isoform delta(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM274638(N-(6-(2-(4-fluorophenyl) imidazo[1,2-a]pyridin-3-y...)
Affinity DataIC50: 1.61nMpH: 7.4 T: 2°CAssay Description:The kinase assay was performed in V-bottom 384-well plates. The final assay volume was 30 μl prepared from 15 μl additions of enzyme, subst...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2018
Entry Details
US Patent

TargetCasein kinase I isoform epsilon(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM274638(N-(6-(2-(4-fluorophenyl) imidazo[1,2-a]pyridin-3-y...)
Affinity DataIC50: 17.2nMpH: 7.4 T: 2°CAssay Description:The kinase assay was performed in V-bottom 384-well plates. The final assay volume was 30 μl prepared from 15 μl additions of enzyme, subst...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2018
Entry Details
US Patent