BDBM275241 1-[(1S)-2-(1-methylethoxy)- 1-phenylethyl]-3-[1-(2- methylpyridin-4-yl)-1H- pyrazolo[3,4-c]pyridin-5- yl]urea::US9884048, Example 135

SMILES CC(C)OC[C@@H](NC(=O)Nc1cc2cnn(-c3ccnc(C)c3)c2cn1)c1ccccc1

InChI Key InChIKey=HJMJJQZNLHKEOE-OAQYLSRUSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 275241   

TargetMitogen-activated protein kinase 1(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM275241(1-[(1S)-2-(1-methylethoxy)- 1-phenylethyl]-3-[1-(2...)
Affinity DataIC50:  0.790nMAssay Description:Activated ERK2 activity was determined in an IMAP-FP assay (Molecular Devices). Using this assay format, the potency (IC50) of each compound was dete...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent