BDBM275796 5-chloro-4-((5-chloro- 6-isobutoxypyridin- 3-yl)oxy)-N-(N,N- dibutylsulfamoyl)- 2-fluorobenzamide::US10071957, Example 13

SMILES CCCCN(CCCC)S(=O)(=O)NC(=O)c1cc(Cl)c(Oc2cnc(OCC(C)C)c(Cl)c2)cc1F

InChI Key InChIKey=QEDSPJWLPLEROB-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 275796   

TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM275796(5-chloro-4-((5-chloro- 6-isobutoxypyridin- 3-yl)ox...)
Affinity DataIC50:  3.64E+3nMpH: 7.4 T: 2°CAssay Description:Preparation of membranes containing recombinantly expressed sodium channels: Frozen recombinant cell pellets were thawed on ice and diluted to 4 time...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent