BDBM282170 2-(3-carbamoyl-4-(1H-imidazol-1-yl)benzylamino)-N-(3,4-difluorobenzyl)nicotinamide::US10030016, Example 50

SMILES NC(=O)c1cc(CNc2ncccc2C(=O)NCc2ccc(F)c(F)c2)ccc1-n1ccnc1

InChI Key InChIKey=VOKRHGDNGFSIMD-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 282170   

Target3-phosphoinositide-dependent protein kinase 1 [51-359](Human)
Sunesis Pharmaceuticals

US Patent
LigandPNGBDBM282170(2-(3-carbamoyl-4-(1H-imidazol-1-yl)benzylamino)-N-...)
Affinity DataIC50: 5.00E+3nMAssay Description:PDK1 (amino acids 51-359) and AKT2 (amino acids 140-467 fused to PIFtide, amino acids EEQEMFRDFDYIADW) were expressed as N-terminally tagged GST fusi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2018
Entry Details
US Patent