BDBM282902 6-(4-(4-fluorophenyl)-1-(3,3,3-trifluoropropyl)-1H- imidazol-5-yl)imidazo[1,2-b]pyridazine-3-carboxamide::US9884868, Example 107'

SMILES CCc1nc(c([nH]1)-c1ccc2cn[nH]c2c1)-c1ccc(F)c(C)c1

InChI Key InChIKey=DLOUVWMIAXHHQX-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 282902   

TargetTGF-beta receptor type-1(Human)
Rigel Pharmaceuticals

US Patent
LigandPNGBDBM282902(6-(4-(4-fluorophenyl)-1-(3,3,3-trifluoropropyl)-1H...)
Affinity DataIC50: 1.90nMpH: 7.4 T: 2°CAssay Description:Assays for the compounds reported below were conducted in 1536-well plates and 2 mL reactions are prepared from addition of HIS-TGF-βR1 T204D or...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2019
Entry Details
US Patent

TargetTGF-beta receptor type-2(Human)
Rigel Pharmaceuticals

US Patent
LigandPNGBDBM282902(6-(4-(4-fluorophenyl)-1-(3,3,3-trifluoropropyl)-1H...)
Affinity DataIC50: 7.61E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2019
Entry Details
US Patent