BDBM282997 1-(tert-butyl)-3-((6-(1-(2,2-difluoroethyl)-4-(4- fluorophenyl)-1H-imidazol-5-yl)imidazo[1,2- b]pyridazin-3-yl)methyl)urea::US10287295, Example 199'::US11352360, Example 199'::US9884868, Example 199'
SMILES CC(C)(C)NC(=O)NCc1cnc2ccc(nn12)-c1c(ncn1CC(F)F)-c1ccc(F)cc1
InChI Key InChIKey=GUNDQCGSBHUTRO-UHFFFAOYSA-N
Data 6 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 6 hits for monomerid = 282997
Affinity DataIC50: 9.5nMpH: 7.4 T: 2°CAssay Description:Assays for the compounds reported below were conducted in 1536-well plates and 2 mL reactions are prepared from addition of HIS-TGF-βR1 T204D or...More data for this Ligand-Target Pair
Affinity DataIC50: 9.5nMAssay Description:Assays for the compounds reported below were conducted in 1536-well plates and 2 mL reactions are prepared from addition of HIS-TGF-βR1 T204D or...More data for this Ligand-Target Pair
Affinity DataIC50: 1.50E+4nMAssay Description:Assays for the compounds reported below were conducted in 1536-well plates and 2 mL reactions are prepared from addition of HIS-TGF-βR1 T204D or...More data for this Ligand-Target Pair
Affinity DataIC50: 9.5nMAssay Description:Assays for the compounds reported below were conducted in 1536-well plates and 2 mL reactions are prepared from addition of HIS-TGF-βR1 T204D or...More data for this Ligand-Target Pair