BDBM28347 3-(10H-phenothiazin-10-ylmethyl)-1-azabicyclo[2.2.2]octan-1-ium::Mequitazine::ZINC01567421, 6

SMILES C(C1C[NH+]2CCC1CC2)N1c2ccccc2Sc2ccccc12

InChI Key InChIKey=HOKDBMAJZXIPGC-UHFFFAOYSA-O

Data  6 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 28347   

TargetMuscarinic acetylcholine receptor M3(Homo sapiens (Human))
Mayo Foundation

Curated by PDSP Ki Database
LigandPNGBDBM28347(3-(10H-phenothiazin-10-ylmethyl)-1-azabicyclo[2.2....)
Affinity DataKi:  5.30nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
Mayo Foundation

Curated by PDSP Ki Database
LigandPNGBDBM28347(3-(10H-phenothiazin-10-ylmethyl)-1-azabicyclo[2.2....)
Affinity DataKi:  5.60nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H1 receptor(Homo sapiens (Human))
Mayo Foundation

Curated by PDSP Ki Database
LigandPNGBDBM28347(3-(10H-phenothiazin-10-ylmethyl)-1-azabicyclo[2.2....)
Affinity DataKi:  5.80nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M5(Homo sapiens (Human))
Mayo Foundation

Curated by PDSP Ki Database
LigandPNGBDBM28347(3-(10H-phenothiazin-10-ylmethyl)-1-azabicyclo[2.2....)
Affinity DataKi:  11nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M4(Homo sapiens (Human))
Mayo Foundation

Curated by PDSP Ki Database
LigandPNGBDBM28347(3-(10H-phenothiazin-10-ylmethyl)-1-azabicyclo[2.2....)
Affinity DataKi:  11.1nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M2(Homo sapiens (Human))
Mayo Foundation

Curated by PDSP Ki Database
LigandPNGBDBM28347(3-(10H-phenothiazin-10-ylmethyl)-1-azabicyclo[2.2....)
Affinity DataKi:  14nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTrypanothione reductase(Trypanosoma cruzi)
University of Alberta

LigandPNGBDBM28347(3-(10H-phenothiazin-10-ylmethyl)-1-azabicyclo[2.2....)
Affinity DataIC50:  2.18E+4nMpH: 7.5 T: 2°CAssay Description:Inhibition of TryR was carried out in 96-well plates using a Biotek Precision 2000 automated liquid handler. Reaction was initiated by addition of NA...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTrypanothione reductase(Trypanosoma brucei brucei)
University of Alberta

LigandPNGBDBM28347(3-(10H-phenothiazin-10-ylmethyl)-1-azabicyclo[2.2....)
Affinity DataIC50:  5.43E+4nMpH: 7.5 T: 2°CAssay Description:Inhibition of TryR was carried out in 96-well plates using a Biotek Precision 2000 automated liquid handler. Reaction was initiated by addition of NA...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed