BDBM283782 1-(3-chlorophenyl)-3-[4-[(3-fluoroazetidin-3-yl)methyl]phenyl]urea::US10023559, Example 107

SMILES FC1(Cc2ccc(NC(=O)Nc3cccc(Cl)c3)cc2)CNC1

InChI Key InChIKey=OXNVBOGQURZGES-UHFFFAOYSA-N

Data  1 KI  1 Other

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 283782   

TargetTrace amine-associated receptor 1(Rat)
Hoffmann-La Roche

US Patent
LigandPNGBDBM283782(1-(3-chlorophenyl)-3-[4-[(3-fluoroazetidin-3-yl)me...)
Affinity DataKi:  2.60nMpH: 7.4Assay Description:HEK-293 cells stably expressing rat TAAR1 were maintained at 37° C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, heat in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/6/2019
Entry Details
US Patent

TargetTrace amine-associated receptor 1(Mouse)
Hoffmann-La Roche

US Patent
LigandPNGBDBM283782(1-(3-chlorophenyl)-3-[4-[(3-fluoroazetidin-3-yl)me...)
Affinity DatapH: 7.4Assay Description:HEK-293 cells stably expressing mouse TAAR1 were maintained at 37° C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, heat ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/6/2019
Entry Details
US Patent