BDBM28402 1-methyl-4-(6-{3-[(E)-2-(1H-1,2,3,4-tetrazol-5-yl)ethenyl]phenyl}pyrazin-2-yl)-1,4-diazepane::pyrazine inhibitor, 5

SMILES CN1CCCN(CC1)c1cncc(n1)-c1cccc(C=Cc2nnn[nH]2)c1

InChI Key InChIKey=AHOONMAUZAASAZ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 28402   

TargetSerine/threonine-protein kinase pim-2(Human)
Boehringer Ingelheim Pharmaceuticals

LigandPNGBDBM28402(1-methyl-4-(6-{3-[(E)-2-(1H-1,2,3,4-tetrazol-5-yl)...)
Affinity DataIC50: 160nMpH: 7.5 T: 2°CAssay Description:The activity of Pim kinase was measured in a homogeneous luciferase assay using GST-Pim, biotinylated peptide substrate and a luciferin-luciferase de...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2009
Entry Details Article
PubMed