BDBM28498 (3R,5S)-5-(2-{4-[(4-benzylphenyl)amino]thieno[3,2-d]pyrimidin-6-yl}ethynyl)pyrrolidin-3-yl morpholine-4-carboxylate::alkynyl thienopyrimidine, 15j

SMILES O=C(O[C@H]1CN[C@@H](C1)C#Cc1cc2ncnc(Nc3ccc(Cc4ccccc4)cc3)c2s1)N1CCOCC1

InChI Key InChIKey=QAOIGWCWWITZTC-JWQCQUIFSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 28498   

TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Gsk

LigandPNGBDBM28498((3R,5S)-5-(2-{4-[(4-benzylphenyl)amino]thieno[3,2-...)
Affinity DataIC50:  60nMAssay Description:Assays were performed in 96-well polystyrene round-bottomed plates in reaction buffer containing biotinylated substrate and purified kinase in the pr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Gsk

LigandPNGBDBM28498((3R,5S)-5-(2-{4-[(4-benzylphenyl)amino]thieno[3,2-...)
Affinity DataIC50:  240nMpH: 7.5 T: 2°CAssay Description:Assays were performed in 96-well polystyrene round-bottomed plates in reaction buffer containing biotinylated substrate and purified kinase in the pr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed