BDBM284998 N-[2,4-difluoro-5-[2-methyl-6-(1- methylpyrazol-4-yl)-1-oxoisoquinolin-4-yl] phenyl]methanesulfonamide::US10023592, Example 43

SMILES Cn1cc(cn1)-c1ccc2c(c1)c(cn(C)c2=O)-c1cc(NS(C)(=O)=O)c(F)cc1F

InChI Key InChIKey=GPNYKSPNXFZEEW-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 284998   

TargetBromodomain-containing protein 4(Homo sapiens (Human))
Celgene Quanticel Research

US Patent
LigandPNGBDBM284998(N-[2,4-difluoro-5-[2-methyl-6-(1- methylpyrazol-4-...)
Affinity DataIC50: <500nMpH: 7.3Assay Description:Determination of the IC50 for the heterocyclic derivative BRD4 inhibitors disclosed herein was performed as follows. His-tagged BRD4 was cloned, expr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent