BDBM285027 N-[3-[2-methyl-6-(6-methylpyridin-3-yl)-1- oxoisoquinolin-4-yl]phenyl]ethanesulfonamide::US10023592, Example 72::US10941160, Example 72

SMILES CCS(=O)(=O)Nc1cccc(c1)-c1cn(C)c(=O)c2ccc(cc12)-c1ccc(C)nc1

InChI Key InChIKey=ILUWENTYMZHYSD-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 285027   

TargetBromodomain-containing protein 4(Homo sapiens (Human))
Celgene Quanticel Research

US Patent
LigandPNGBDBM285027(N-[3-[2-methyl-6-(6-methylpyridin-3-yl)-1- oxoisoq...)
Affinity DataIC50: <500nMAssay Description:Determination of the IC50 for the heterocyclic derivative BRD4 inhibitors disclosed herein was performed as follows. His-tagged BRD4 was cloned, expr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBromodomain-containing protein 4(Homo sapiens (Human))
Celgene Quanticel Research

US Patent
LigandPNGBDBM285027(N-[3-[2-methyl-6-(6-methylpyridin-3-yl)-1- oxoisoq...)
Affinity DataIC50: <500nMpH: 7.3Assay Description:Determination of the IC50 for the heterocyclic derivative BRD4 inhibitors disclosed herein was performed as follows. His-tagged BRD4 was cloned, expr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent