BDBM285286 2-[[3-(1,5-dimethyl-6-oxopyridin-3-yl)-5- methylsulfonylphenoxy]methyl]benzonitrile::BDBM486130::US10023592, Example 334

SMILES Cc1cc(cn(C)c1=O)-c1cc(OCc2ccccc2C#N)cc(c1)S(C)(=O)=O

InChI Key InChIKey=JFWHIYWRVFGTSR-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 285286   

TargetBromodomain-containing protein 4(Homo sapiens (Human))
Celgene Quanticel Research

US Patent
LigandPNGBDBM285286(2-[[3-(1,5-dimethyl-6-oxopyridin-3-yl)-5- methylsu...)
Affinity DataIC50: <500nMAssay Description:Determination of the IC50 for the heterocyclic derivative BRD4 inhibitors disclosed herein was performed as follows. His-tagged BRD4 was cloned, expr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBromodomain-containing protein 4(Homo sapiens (Human))
Celgene Quanticel Research

US Patent
LigandPNGBDBM285286(2-[[3-(1,5-dimethyl-6-oxopyridin-3-yl)-5- methylsu...)
Affinity DataIC50: <500nMpH: 7.3Assay Description:Determination of the IC50 for the heterocyclic derivative BRD4 inhibitors disclosed herein was performed as follows. His-tagged BRD4 was cloned, expr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent