BDBM285428 N-[5-[3-(methanesulfonamido)phenyl]-1- methyl-2-oxopyridin-3-yl]acetamide::US10023592, Example 482

SMILES CC(=O)Nc1cc(cn(C)c1=O)-c1cccc(NS(C)(=O)=O)c1

InChI Key InChIKey=JPZAAGFNKWCAFH-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 285428   

TargetBromodomain-containing protein 4(Human)
Celgene Quanticel Research

US Patent
LigandPNGBDBM285428(US10023592, Example 482 | N-[5-[3-(methanesulfonam...)
Affinity DataIC50: 5.00E+3nMpH: 7.3Assay Description:Determination of the IC50 for the heterocyclic derivative BRD4 inhibitors disclosed herein was performed as follows. His-tagged BRD4 was cloned, expr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2019
Entry Details
US Patent