BDBM285580 US10077269, Example 53::US10669279, Example 53::US9598421, Example 53::azetidin-1-yl[3-(4-fluoro-3,5-dimethylphenyl)imidazo[1,2-b]pyridazin-2-yl]methanone

SMILES Cc1cc(cc(C)c1F)-c1c(nc2cccnn12)C(=O)N1CCC1

InChI Key InChIKey=CTXZJNXACMKAGH-UHFFFAOYSA-N

Data  12 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 12 hits for monomerid = 285580   

LigandPNGBDBM285580(US10077269, Example 53 | azetidin-1-yl[3-(4-fluoro...)
Affinity DataIC50: 17.8nMAssay Description:The PDE4A3, PDE4B1, PDE4C1 and PDE4D3 assays use the Scintillation Proximity Assay (SPA) technology to measure the inhibition of human recombinant PD...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2019
Entry Details
US Patent

LigandPNGBDBM285580(US10077269, Example 53 | azetidin-1-yl[3-(4-fluoro...)
Affinity DataIC50: 17.8nMAssay Description:The PDE4A3, PDE4B1, PDE4C1 and PDE4D3 assays use the Scintillation Proximity Assay (SPA) technology to measure the inhibition of human recombinant PD...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2019
Entry Details
US Patent

LigandPNGBDBM285580(US10077269, Example 53 | azetidin-1-yl[3-(4-fluoro...)
Affinity DataIC50: 17.8nMAssay Description:Human PDE4A3 coding sequence (amino acids 2 to 825 from the sequence with accession number NP_001104779) was cloned into the baculovirus expression v...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details
US Patent

LigandPNGBDBM285580(US10077269, Example 53 | azetidin-1-yl[3-(4-fluoro...)
Affinity DataIC50: 63.3nMAssay Description:Human PDE4A3 coding sequence (amino acids 2 to 825 from the sequence with accession number NP_001104779) was cloned into the baculovirus expression v...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details
US Patent

LigandPNGBDBM285580(US10077269, Example 53 | azetidin-1-yl[3-(4-fluoro...)
Affinity DataIC50: 63.3nMAssay Description:The PDE4A3, PDE4B1, PDE4C1 and PDE4D3 assays use the Scintillation Proximity Assay (SPA) technology to measure the inhibition of human recombinant PD...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2019
Entry Details
US Patent

LigandPNGBDBM285580(US10077269, Example 53 | azetidin-1-yl[3-(4-fluoro...)
Affinity DataIC50: 63.3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2019
Entry Details
US Patent

LigandPNGBDBM285580(US10077269, Example 53 | azetidin-1-yl[3-(4-fluoro...)
Affinity DataIC50: 153nMAssay Description:Human PDE4A3 coding sequence (amino acids 2 to 825 from the sequence with accession number NP_001104779) was cloned into the baculovirus expression v...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details
US Patent

LigandPNGBDBM285580(US10077269, Example 53 | azetidin-1-yl[3-(4-fluoro...)
Affinity DataIC50: 153nMAssay Description:The PDE4A3, PDE4B1, PDE4C1 and PDE4D3 assays use the Scintillation Proximity Assay (SPA) technology to measure the inhibition of human recombinant PD...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2019
Entry Details
US Patent

LigandPNGBDBM285580(US10077269, Example 53 | azetidin-1-yl[3-(4-fluoro...)
Affinity DataIC50: 153nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2019
Entry Details
US Patent

LigandPNGBDBM285580(US10077269, Example 53 | azetidin-1-yl[3-(4-fluoro...)
Affinity DataIC50: 3.11E+3nMAssay Description:Human PDE4A3 coding sequence (amino acids 2 to 825 from the sequence with accession number NP_001104779) was cloned into the baculovirus expression v...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details
US Patent

LigandPNGBDBM285580(US10077269, Example 53 | azetidin-1-yl[3-(4-fluoro...)
Affinity DataIC50: 3.11E+3nMAssay Description:The PDE4A3, PDE4B1, PDE4C1 and PDE4D3 assays use the Scintillation Proximity Assay (SPA) technology to measure the inhibition of human recombinant PD...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2019
Entry Details
US Patent

LigandPNGBDBM285580(US10077269, Example 53 | azetidin-1-yl[3-(4-fluoro...)
Affinity DataIC50: 3.11E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2019
Entry Details
US Patent