BDBM287582 US9567324, 22

SMILES Cc1ccc(F)c(NC(=O)c2cccc(c2)C#Cc2cc(cnc2N)C(=O)N=S2(=O)CCOCC2)c1

InChI Key InChIKey=LFNAERHMPRGPKC-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 287582   

TargetVascular endothelial growth factor receptor 2(Human)
Allergan

US Patent
LigandPNGBDBM287582(US9567324, 22)
Affinity DataIC50: 14nMpH: 7.4Assay Description:Biochemical KDR kinase assays were performed in 96 well microtiter plates that were coated overnight with 75 μg/well of poly-Glu-Tyr (4:1) in 10...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/17/2019
Entry Details
US Patent

TargetPlatelet-derived growth factor receptor beta(Human)
Allergan

US Patent
LigandPNGBDBM287582(US9567324, 22)
Affinity DataIC50: 11nMpH: 7.4Assay Description:Biochemical PDGFRβ kinase assays were performed in 96 well microtiter plates that were coated overnight with 75 μg of poly-Glu-Tyr (4:1) in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/17/2019
Entry Details
US Patent